WebMar 1, 1998 · Under these circumstances, four major approaches can assist in evaluation of assay interference: (a) measure TSH by a sensitive immunometric method; (b) measure … WebApr 10, 2024 · Subsequently, assay specificity improved and TSH assay “quality” became synonymous with the method's sensitivity, ... it is more difficult to eliminate falsely high …
Falsely diagnosed thyrotoxicosis caused by anti-streptavidin …
WebNov 19, 2014 · A female patient with rheumatoid arthritis who had persistently and grossly elevated thyroid stimulating hormone (TSH) but normal free thyroxine in electrochemiluminescent assays is reported, the first report of anti-ruthenium antibodies selectively interfering with a TSH assay and causing erratic gross elevation of TSH … WebTherefore, it was confirmed that the presence of heterophilic antibodies in the patient samples interfered with the TSH measurements in multiple assay systems. Conclusions: … jimmy the beef
Anti-ruthenium antibodies mimic macro-TSH in electrochemiluminescent …
WebBiotin is used together with streptavidin in the design of many diagnostic assays. These assays leverage the high stability and specificity of the biotin-streptavidin interaction as a means of increasing analytic sensitivity. Examples of assays that may use biotin-streptavidin chemistry include those that measure cardiac biomarkers and hormones. WebMay 23, 2024 · In conclusion, the ingestion of 20 mg or more of biotin may lead to a clinically relevant thyroid assay interference. The clinicians must take this point in consideration before assessing the results of any thyroid function tests. Home; ... TSH: Thyroid-Stimulating Hormone, FT4: Free Thyroxine, FT3: Free Triiodothyronine, TT4 ... WebOct 16, 2024 · We had only measures of TSH, free T 4, and TPOAb during pregnancy (mostly in the first half of pregnancy), and measurements were performed using different assays among cohorts. While the absolute concentrations of TSH and free T 4 can vary between assays, we defined the outcomes by population- and assay-specific cutoffs to overcome … jimmy the cat dupree