WebNov 11, 2014 · The supernatant was recovered, and the protein concentration was determined by the Bradford protein assay (Bio-Rad, Hercules, CA). 30 μg/μl protein was … WebAlibaba
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WebDec 24, 2024 · Mitogen-activated protein kinase, kinase, kinase- 19 (MAP3K19) was recently shown to be upregulated in IPF and this MAPK has a key role in target gene transcription in the TGF-β pathway. Herein, we further investigate the role of MAP3K19 in cultured normal and IPF fibroblasts and in a humanized SCID mouse model of IPF employing both short ... WebFeb 18, 2024 · Background Idiopathic pulmonary fibrosis (IPF) is a chronic and ultimately fatal disease characterized by a progressive decline in lung function. Fibrotic diseases, such as IPF, are characterized by uncontrolled activation of fibroblasts. Since the microenvironment is known to affect cell behavior, activated fibroblasts can in turn …
WebAccording to recent studies,Pheretima has anti-pulmonary and anti-renal interstitial fibrosis,respiratory syncytial virus-inhibiting,human hypertrophic scar fibroblast proliferation-suppressing,and mouse embryonic fibroblast proliferation-promoting effects. WebJan 16, 2008 · Cells have developed many kinds of protective mechanisms to cope with stress damage such as heat shock proteins (HSP), glucose-response protein (GRP), and growth arrest and DNA damage (GADD) gene families. It is now clear that cellular response to oxidative stress is a universal phenomenon.
WebMar 20, 2024 · Proteins and peptides are the main components of Pheretima, occupying 55–60% of the total weight, and they are also the important active ingredients with anticoagulant, anti-stroke, antibacterial, and antifibrotic activities, etc. [1]. Additionally, the primary structure of protein is highly stable in the processing of medicinal materials [13, 14]. WebOct 6, 2024 · Pheretima was the dried bodies from the species of Pheretima aspergillum ( Amynthas aspergillum ), P. vulgaris ( Metaphire vulgaris ), P. guillemi ( M. guillemi ), and P. …
WebMar 1, 2024 · Download Citation Novel Pheretima guillelmi-derived antithrombotic protein DPf3: Identification, characterization, in vitro evaluation and antithrombotic mechanisms investigation In this study ...
WebOct 6, 2024 · Pheretima has been used as an animal-derived traditional Chinese medicine for thousands of years in Asian countries due to its multi-activities. However, more than half of the commercial Pheretima are adulterants according to the previous research. Besides, the standards of Pheretima are still inadequate in the identification of Pheretima species. effect of solutes on grain refinementWebApr 20, 2024 · Li et al. (2024) found that the purified protein (P2) isolated from P. aspergillum showed great regulatory effect on TGF-β/Smad pathway in MRC-5 cells induced by TGF-β1, a finding that provides ... effect of solar flares to solar panelsWebPheretima vulgaris Chen ( P. vulgaris ), widely used in China, is a species of earthworm in the Chinese pharmacopoeia and has been rarely studied. Hence, the purification of active protein monomer, and antithrombotic evaluation and mechanisms investigation are needed. containerships rhoonWebOct 4, 2024 · The tissues of Pheretima spp. contain large amounts of microelements, Zn 59.1 μg/g, Cu 25.4 μg/g, Fe 1735.5 μg/g, Cr 10.93 μg/g, Mo 0.25 μg/g, Ca 1019.2 μg/g and Mn 1143 μg/g [ 29 ]. These of Allolobophora caliginosa contain crude protein 57.96%; crude fat 6.53%, crude ash 21.09%, crude fiber 0.36%, and N extract 14.06%. container ship spot priceWebMar 25, 2024 · Materials and methods 2.1. Drugs and reagents. Bleomycin hydrochloride for injection (#H20055833) was provided by Hanhui Pharmaceutical Co.,... 2.2. Preparation of … containerships routesWebApr 1, 2024 · 表3 参环毛蚓、通俗环毛蚓、赤子爱胜蚓乙醇沉淀物的纤溶比活、抗凝比活与蛋白含量(n＝3)Tab 3 Specific activity of fibrinolysis，specific activity of anticoagulation and protein content of ethanol precipitates from Pheretima aspergillum，Pheretima vulgaris and Eisenia fetida (n＝3) 3.4 SDS-PAGE 结果分析 effect of solar energyWebNov 15, 2013 · The coelomic fluid protein from Pheretima posthuman earthworm prevented MCF-7 cells growth, with an IC 50 value of 0.26 mg/ml (MW 15 kDa; Verma and Sobha, … containerships rotterdam