Cholesteryl teg
WebDec 24, 2009 · We used a cholesteryl-TEG anchor first described by Pfeiffer and Hook (J. Am. Chem. Soc. 2004, 126, 10224-10225). The cholesterol-based anchor molecules … WebCholesteryl TEG - (O-0095) This modification is available as part of a custom oligonucleotide configuration. Please use OLIGObuilder™ to generate pricing and order …
Cholesteryl teg
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WebAug 11, 2024 · As expected, cholesteryl-TEG-modified oligonucleotides interact more efficiently with lipid-based membrane surfaces (Figure 1F and Figure S4, Supporting Information) than nucleic acid probes without the cholesteryl moiety, for all the systems tested. 2.2 Photophysical Properties of FRET Active DNA-Grafted QS WebApr 14, 2007 · We introduce a rapid, simple one-step procedure for the high-yield immobilization of cholesteryl-tetraethyleneglycol-modified oligonucleotides (chol-DNA) …
WebModification of siRNA with 5′ Cholesteryl TriEthylene Glycol (Chol-TEG) promotes cellular uptake by hemocytes, nearly eightfold over that of unmodified siRNA. FACS analysis … WebCholesteryl-teg cep C70H106N3O11P CID 78319523 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, …
WebCholesterol TEG Modification is a lipophilic modification aiding in cellular delivery. The TEG liker arm facilitates solubility issues of the oligo making it soluble in aqueous … http://www.bioligo.com/cn/detail/226
WebCholesteryl-conjugated oligonucleotides have been the subject of substantial interest in antisense and other studies due to the lipophilicity and good availability of cholesterol. …
WebThe addition of lipophilic groups to an oligonucleotide would be expected to enhance cellular uptake/membrane permeation. The use of cholesteryl oligos and the consequent improvement in activity has been described. We have designed our Cholesteryl products with triethyleneglycol (TEG) spacers for maximum solubility. sap vmware cloudWebDescription: 3'-Cholesteryl-TEG CPG. 1-Dimethoxytrityloxy-3-O- (N-cholesteryl-3-aminopropyl)-triethyleneglycol-. glyceryl-2-O-succinoyl-long chain alkylamino-CPG. F.W.: 755.97. Diluent: Not Applicable. Coupling: This support should be used in a manner identical to normal protected nucleoside support since it contains the DMT group. short tuesday quotesshort tucked layered bobWebMar 5, 2024 · Cholesteryl-TEG-modified aptamers were embedded into the liposomal lipid bilayer while the interior cavity of the liposomes encapsulated fluorescent sulforhodamine B dye. Such liposomes ... sap vs amb live scoreWebCholesterol-PEG 600 has been used to evaluate its ability to induce apoptosis in vascular smooth muscle cells. [ 3] It has also been used to restore cholesterol following depletion by methyl β-cyclodextrin. [ 4] Packaging 250, 500 mg in serum bottle 1, 5 g in serum bottle Biochem/physiol Actions sap visual enterprise author anleitungWebThe addition of lipophilic groups to an oligonucleotide would be expected to enhance cellular uptake/membrane permeation. The use of cholesteryl oligos and the consequent improvement in activity has been described. We have designed our Cholesteryl products with triethyleneglycol (TEG) spacers for maximum solubility. 3 Product Results Sort by: … sap visual enterprise author trialWebCholesteryl-TEG. Cholesteryl-TEG is often used to increase the cell uptake of oligonucleotide. This modification has been shown to elicit cell uptake both in vitro and … sap vocational training