Web4. Payoda Module No. 120/ 2, 1st Floor, North Block, Elcot SEZ, Tidel Park, Coimbatore IT Park Road, Coimbatore, Tamil Nadu, India 641014 Coordinate: 11.0321843501 ... WebFunction. Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the ...
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WebJun 17, 2015 · Author Summary In the model yeasts and filamentous fungi, CDC2 is an essential gene that encodes the only CDK essential for mitotic cell cycle progression. However, the wheat scab fungus F. graminearum contains two CDC2 orthologs. The cdc2A and cdc2B deletion mutants had no defects in vegetative growth but deletion of both is … WebCHROMOSOMAL LOCATION Genetic locus: CDC2 (human) mapping to 10q21.2; Cdc2a (mouse) mapping to 10 B5.3. SOURCE Cdc2 p34 (B-6) iis a mouse monoclonal antibody specific for an epitope mapping between amino acids 2-30 near the N-terminus of Cdc2 p34 of human origin. PRODUCT Each vial contains 200 µg IgG 1 kappa light chain in 1.0 ml … uncp account login
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WebNov 19, 2024 · The two cDC2 subsets express distinct patterns of genes encoding Toll-like receptors, chemokines and chemokine receptors. T-bet – cDC2s have a more pro … WebAdditional monocyte-derived cells (MCs) with DC-like properties (moDCs) can be generated during pathogen-initiated inflammation via the differentiation of monocytes [ 6 ]. Figure 2. Dendritic cell development. … WebJun 17, 2015 · The cdc2A and cdc2B mutants had no obvious defects in growth rate and conidiation but deletion of both of them is lethal, indicating that these two CDC2 orthologs have redundant functions during vegetative growth and asexual reproduction. However, whereas the cdc2B mutant was normal, the cdc2A mutant was significantly reduced in … un cow-boy a paris